2699768-78-8
2699768-78-8
Chemical Structure
ARN24139
- CAS No.: 2699768-78-8
- Formula:C24H16F3N3O4S
- Molecular Weight:499.46
IUPAC Name: 4,6-dioxo-1,3-diphenyl-2-thioxo-N-(3-(trifluoromethoxy)phenyl)hexahydropyrimidine-5-carboxamide
InChIKey: MGLUIWLWLIJXMY-UHFFFAOYSA-N
SMILES: O=C(C1C(N(C(N(C2=CC=CC=C2)C1=O)=S)C3=CC=CC=C3)=O)NC4=CC(OC(F)(F)F)=CC=C4
Biological Activity: ARN24139(compound 3f) is a topoisomerase II (topoII) inhibitor with the IC50 of 7.3 μM. ARN24139 can inhibit cancer cell proliferation and is well tolerated in vivo[1].
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ARN24139 | ARN24139(compound 3f) is a topoisomerase II (topoII) inhibitor with the IC50 of 7.3 μM. ARN24139 can inhibit cancer cell proliferation and is well tolerated in vivo. | |||||||||||||||||||||
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References
Keywords
