2713301-38-1
2713301-38-1
Chemical Structure
Desloratadine-3,3,5,5-d4
- CAS No.: 2713301-38-1
- Formula:C19H15D4ClN2
- Molecular Weight:314.85
IUPAC Name: 8-chloro-11-(piperidin-4-ylidene-3,3,5,5-d4)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
InChIKey: JAUOIFJMECXRGI-OSEHSPPNSA-N
SMILES: ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4C([2H])([2H])CNCC/4([2H])[2H])=C1
Biological Activity: Desloratadine-3,3,5,5-d4 is the deuterium labeled Desloratadine. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities[1][2].
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Desloratadine-3,3,5,5-d4 | Desloratadine-3,3,5,5-d4 is the deuterium labeled Desloratadine. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities. | |||||||||||||||||||||
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Desloratadine (Standard) | ≥98% | Desloratadine (Standard) is the analytical standard of Desloratadine. This product is intended for research and analytical applications. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities. | ||||||||||||||||||||
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Desloratadine-d4 | Desloratadine-d4 is the deuterium labeled Desloratadine. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities. | |||||||||||||||||||||
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Desloratadine-d5 | 95.33% | Desloratadine-d5 is deuterium labeled Desloratadine. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities. | ||||||||||||||||||||
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Desloratadine-d9 | Desloratadine-d9 is the deuterium labeled Desloratadine. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities. | |||||||||||||||||||||
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Desloratadine-d4 hydrobromide | Desloratadine-d4 hydrobromide is deuterated labeled Desloratadine (HY-B0539). Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities. | |||||||||||||||||||||
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Desloratadine | 99.98% | Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist (Ki=0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria. | ||||||||||||||||||||
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