2724937-55-5
Chemical Structure
EOS-984
- CAS No.: 2724937-55-5
- Formula:C33H47N3O9
- Molecular Weight:629.74
InChIKey: VIUYKJLZCCMVQW-RUZDIDTESA-N
SMILES: COC1=CC(C(O[C@@H]2CCCOC3=C(C(OC)=CC(C(NCCCN4CCCN(CC4)CC2)=O)=C3)OC)=O)=CC(OC)=C1OC
Biological Activity: EOS-984 is a macrocyclic diamine equilibrative nucleoside transporter 1 (ENT1) inhibitor. EOS984 inhibits ENT1 and ENT1-mediated nucleoside transport, restricting adenosine entry into cells via ENT1, thereby attenuating ATP-derived adenosine-mediated T cell immunosuppression and restoring primary human T cell proliferation. EOS984 can be used in research related to ENT1-mediated nucleoside transport, adenosine-related immunosuppression, and tumor immunity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EOS-984 | 99.98% | EOS-984 is a macrocyclic diamine equilibrative nucleoside transporter 1 (ENT1) inhibitor. EOS984 inhibits ENT1 and ENT1-mediated nucleoside transport, restricting adenosine entry into cells via ENT1, thereby attenuating ATP-derived adenosine-mediated T cell immunosuppression and restoring primary human T cell proliferation. EOS984 can be used in research related to ENT1-mediated nucleoside transport, adenosine-related immunosuppression, and tumor immunity. | ||||||||||||||||||||
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