2739938-35-1
Chemical Structure
NH2-C5-PEG4-N3-L-Lysine-PEG3-N3
- CAS No.: 2739938-35-1
- Formula:C25H49N9O9
- Molecular Weight:619.71
IUPAC Name: (S)-N-(18-amino-1-azido-13-oxo-3,6,9-trioxa-12-azaoctadecan-14-yl)-1-azido-3,6,9,12-tetraoxapentadecan-15-amide
InChIKey: CHUDRVBSOKGAET-QHCPKHFHSA-N
SMILES: O=C([C@H](CCCCN)NC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)NCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 | 98.59% | NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Keywords
