2741856-68-6
Chemical Structure
Synucleozid hydrochloride
Synonym(s): NSC 377363 hydrochloride
- CAS No.: 2741856-68-6
- Formula:C22H21ClN6
- Molecular Weight:404.90
IUPAC Name: 2-(4-((4-carbamimidoylphenyl)amino)phenyl)-1H-indole-6-carboximidamide hydrochloride
InChIKey: GKVDOKIPCRSEMM-UHFFFAOYSA-N
SMILES: N=C(C1=CC2=C(C=C1)C=C(C3=CC=C(NC4=CC=C(C(N)=N)C=C4)C=C3)N2)N.Cl
Biological Activity: Synucleozid hydrochloride (NSC 377363 hydrochloride) is a potent inhibitor of the?SNCA?mRNA?that encodes α-synuclein protein. Synucleozid selectively?targets the?α-synuclein?mRNA 5′ UTR at the designed IRE site, decreases the amount of?SNCA?mRNA loaded into polysomes and thereby inhibits?SNCA?translation. Synucleozid has the potential for the investigation of Parkinson’s disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Synucleozid hydrochloride | 98.23% | Synucleozid hydrochloride (NSC 377363 hydrochloride) is a potent inhibitor of the?SNCA?mRNA?that encodes α-synuclein protein. Synucleozid selectively?targets the?α-synuclein?mRNA 5′ UTR at the designed IRE site, decreases the amount of?SNCA?mRNA loaded into polysomes and thereby inhibits?SNCA?translation. Synucleozid has the potential for the investigation of Parkinson’s disease. | ||||||||||||||||||||
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Keywords
