2760326-29-0
2760326-29-0
Chemical Structure
c-Met-IN-9
- CAS No.: 2760326-29-0
- Formula:C25H19F2N5O3
- Molecular Weight:475.45
IUPAC Name: N-(4-((2-(cyclopropanecarboxamido)pyridin-4-yl)oxy)-3-fluorophenyl)-1-(4-fluorophenyl)-1H-imidazole-4-carboxamide
InChIKey: XKFKDNWKGHBQOF-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C2=CC=C(F)C=C2)C=N1)NC3=CC=C(OC4=CC(NC(C5CC5)=O)=NC=C4)C(F)=C3
Biological Activity: c-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities[1].
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c-Met-IN-9 | c-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities. | |||||||||||||||||||||
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References
Keywords
