2761149-17-9
2761149-17-9
Chemical Structure
hAChE/Aβ1-42-IN-1
- CAS No.: 2761149-17-9
- Formula:C20H24N6O
- Molecular Weight:364.44
IUPAC Name: 3-(4-benzylpiperazin-1-yl)-N-(1H-pyrazolo[3,4-b]pyridin-3-yl)propanamide
InChIKey: KDMZZYWXGOGWFK-UHFFFAOYSA-N
SMILES: O=C(NC1=NNC2=NC=CC=C21)CCN3CCN(CC3)CC4=CC=CC=C4
Biological Activity: hAChE/Aβ1-42-IN-1 (Compound 16) is a potent inhibitor of hAChE and Aβ1-42 aggregation. hAChE/Aβ1-42-IN-1 shows acceptable relative safety upon hepG2 cell line and excellent BBB penetration with wide safety margin. hAChE/Aβ1-42-IN-1 has the potential for the research of Alzheimer disease (AD)[1].
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hAChE/Aβ1-42-IN-1 | hAChE/Aβ1-42-IN-1 (Compound 16) is a potent inhibitor of hAChE and Aβ1-42 aggregation. hAChE/Aβ1-42-IN-1 shows acceptable relative safety upon hepG2 cell line and excellent BBB penetration with wide safety margin. hAChE/Aβ1-42-IN-1 has the potential for the research of Alzheimer disease (AD). | |||||||||||||||||||||
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References
Keywords
