hAChE/Aβ1-42-IN-1
hAChE/Aβ1-42-IN-1 (Compound 16) is a potent inhibitor of hAChE and Aβ1-42 aggregation. hAChE/Aβ1-42-IN-1 shows acceptable relative safety upon hepG2 cell line and excellent BBB penetration with wide safety margin. hAChE/Aβ1-42-IN-1 has the potential for the research of Alzheimer disease (AD).
For research use only. We do not sell to patients.
- CAS No.: 2761149-17-9
- Formula: C20H24N6O
- Molecular Weight:364.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AChE |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
25 μM
Compound: 16
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Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
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[PMID: 35101650] |
Chemical Information
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CAS No. 2761149-17-9
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Molecular Weight 364.44
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Formula C20H24N6O
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SMILES
O=C(NC1=NNC2=NC=CC=C21)CCN3CCN(CC3)CC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hAChE/Aβ1-42-IN-1 Related Classifications
HY-144389 Related Classifications
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