2761259-22-5
2761259-22-5
Chemical Structure
PDGFRα/FLT3-ITD-IN-3
- CAS No.: 2761259-22-5
- Formula:C26H39N9
- Molecular Weight:477.65
IUPAC Name: 2-hydroxy-6,6-dimethylspiro[3.5]nonan-7-one
InChIKey: GSQNTGGWLBUZMI-XGAFWQRZSA-N
SMILES: NCCCCNC1=CC=C(C=C1)NC2=NC(N[C@H]3CC[C@@H](CC3)N)=NC4=C2N=CN4C5CCCC5
Biological Activity: PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
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PDGFRα/FLT3-ITD-IN-3 | PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia. | |||||||||||||||||||||
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References
Keywords
