2762302-75-8
Chemical Structure
DENV-IN-4
- CAS No.: 2762302-75-8
- Formula:C28H32N4O4Si
- Molecular Weight:516.66
IUPAC Name: tert-butyl (4-iodophenyl)(methyl)carbamate
InChIKey: ZDPOOVOOOPKULV-IZZNHLLZSA-N
SMILES: O=C1[C@@](CC2=CC=CC=C23)([H])N3[C@](C4=CC=C(C=C4)O[Si](C)(C)C(C)(C)C)([H])N1NC5=CC=C(C=C5)[N+]([O-])=O
Biological Activity: DENV-IN-4 is a potent DENV inhibitor (DENV EC50=4.79 μM, Vero CC50>100 μM, SI>20.9). DENV-IN-4 can inhibit the expression level of DENV2 with concentration-dependence and reduce RNA-dependent RNA polymerase (RdRp) enzymatic activity. DENV-IN-4 has antiviral effect[1].
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DENV-IN-4 | DENV-IN-4 is a potent DENV inhibitor (DENV EC50=4.79 μM, Vero CC50>100 μM, SI>20.9). DENV-IN-4 can inhibit the expression level of DENV2 with concentration-dependence and reduce RNA-dependent RNA polymerase (RdRp) enzymatic activity. DENV-IN-4 has antiviral effect. | |||||||||||||||||||||
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Keywords