2762315-39-7
Chemical Structure
TRPC5-IN-4
- CAS No.: 2762315-39-7
- Formula:C18H11ClF4N4O3
- Molecular Weight:442.75
IUPAC Name: (2R,3R,4S,5S,6R)-2-(((1R,2S,5R)-5-((S)-1,2-dihydroxypropan-2-yl)-2-methylcyclohexyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: OCZQLQZPYCOVIK-UHFFFAOYSA-N
SMILES: O=C1NC(C(N2CCC3=C(N=CN=C3OC4=C(C=C(C=C4)F)C(F)(F)F)C2)=C1Cl)=O
Biological Activity: TRPC5-IN-4 is potent and safe TRPC inhibitor with IC50 value of 14.07 nM and 65 nM for TRPC5 and TRPC4, respectively. TRPC5-IN-4 shows no damage on the cellular component of liver and kidney. TRPC5-IN-4 can be used for the research of chronic kidney disease (CKD)[1].
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TRPC5-IN-4 | TRPC5-IN-4 is potent and safe TRPC inhibitor with IC50 value of 14.07 nM and 65 nM for TRPC5 and TRPC4, respectively. TRPC5-IN-4 shows no damage on the cellular component of liver and kidney. TRPC5-IN-4 can be used for the research of chronic kidney disease (CKD). | |||||||||||||||||||||
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Keywords
