2767011-00-5
2767011-00-5
Chemical Structure
BI 7446
- CAS No.: 2767011-00-5
- Formula:C20H22FN9O10P2S2
- Molecular Weight:693.52
InChIKey: DAWAAQFAHQWLHI-UWLLIWRMSA-N
SMILES: O[C@H]1[C@@H](O2)[C@H](N3C(C=NNC4=O)=C4N=C3)O[C@@H]1CO[P@](O[C@H]5[C@@H](F)[C@H](N6C(N=CN=C7N)=C7N=C6)O[C@@H]5CO[P@]2(S)=O)(S)=O
Biological Activity: BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. BI 7446 can activate all five STING variants in cells and induce tumor-specific immune-mediated tumor rejection. BI 7446 can be used for immuno-oncology research[1].
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BI 7446 | BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. BI 7446 can activate all five STING variants in cells and induce tumor-specific immune-mediated tumor rejection. BI 7446 can be used for immuno-oncology research. | |||||||||||||||||||||
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References
Keywords
