2770246-31-4
2770246-31-4
Chemical Structure
HSD17B13-IN-79
- CAS No.: 2770246-31-4
- Formula:C19H12Cl2F3N3O4S
- Molecular Weight:506.28
InChIKey: DSNYQOSZTNNPHJ-UHFFFAOYSA-N
SMILES: ClC1=C(O)C(Cl)=CC(C(NC2=C(C(NCC3=CC=CC=C3OC(F)(F)F)=O)N=CS2)=O)=C1
Biological Activity: HSD17B13-IN-79 (Compound 32) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-79 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-79 | HSD17B13-IN-79 (Compound 32) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-79 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
