2771319-69-6
Chemical Structure
BAY-3153
- CAS No.: 2771319-69-6
- Formula:C25H29Cl2N3O4
- Molecular Weight:506.42
IUPAC Name: ((1R,5S)-9-(4-chloro-3-ethoxyphenyl)-3-oxa-7,9-diazabicyclo[3.3.1]nonan-7-yl)((2R,4S)-1-(4-chlorophenyl)-4-hydroxypyrrolidin-2-yl)methanone
InChIKey: LZSPYTNDRPEZBK-OQLXKQOESA-N
SMILES: O[C@H](C1)C[C@H](C(N2C[C@H]3N(C4=CC=C(Cl)C(OCC)=C4)[C@H](COC3)C2)=O)N1C5=CC=C(Cl)C=C5
Biological Activity: BAY-3153, a chemical probe, is a selective CCR1 (C-C motif chemokine receptor 1) antagonist (human IC50=3 nM; rat IC50=11 nM; mice IC50=81 nM)[1].
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BAY-3153 | BAY-3153, a chemical probe, is a selective CCR1 (C-C motif chemokine receptor 1) antagonist (human IC50=3 nM; rat IC50=11 nM; mice IC50=81 nM). | |||||||||||||||||||||
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Keywords