2. GPCR/G Protein Immunology/Inflammation
  3. CCR
  4. BAY-3153

BAY-3153 is a selective CCR1 (C-C motif chemokine receptor 1) antagonist (human IC50=3 nM; rat IC50=11 nM; mice IC50=81 nM).

For research use only. We do not sell to patients.

BAY-3153 Chemical Structure

BAY-3153 Chemical Structure

CAS No. : 2771319-69-6

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BAY-3153 Related Antibodies

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

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Description

BAY-3153 is a selective CCR1 (C-C motif chemokine receptor 1) antagonist (human IC50=3 nM; rat IC50=11 nM; mice IC50=81 nM)[1].

In Vivo

BAY-3153 (10 mg/kg) treatment shows reduction of infiltrating macrophages in experimental renal ischemia/reperfusion model in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

506.42

Formula

C25H29Cl2N3O4
CAS No.
SMILES

O[C@H](C1)C[C@H](C(N2C[C@H]3N(C4=CC=C(Cl)C(OCC)=C4)[C@H](COC3)C2)=O)N1C5=CC=C(Cl)C=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BAY-3153 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAY-31532771319-69-6BAY3153BAY 3153CCRCC chemokine receptorinfiltrating macrophageInhibitorinhibitorinhibit

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