2778229-31-3
Chemical Structure
Mal-va-mac-SN38
- CAS No.: 2778229-31-3
- Formula:C52H61N7O14S
- Molecular Weight:1040.14
InChIKey: SOAJQWUCIOZQQL-VKSGSTCWSA-N
SMILES: O=C(N(COC1=CC=C(N=C(C(N2C3)=CC([C@@](O)(CC)C(OC4)=O)=C4C2=O)C3=C5CC)C5=C1)CCS(=O)(C)=O)OCC6=CC=C(NC([C@@H](NC([C@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)C)=O)C=C6
Biological Activity: Mal-va-mac-SN38 is a drug-linker conjugate for ADC. Mal-va-mac-SN38 contains a ADC cytotoxin SN-38 (HY-13704) and a linker (HY-126364). Mal-va-mac-SN38 can rapidly and covalently bind with endogenous albumin in vivo, resulting in the formation of HSA-va-mac-SN38. Mal-va-mac-SN38 demonstrates exceptional stability in human plasma, and has anti-tumor and anti-metastasis effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Mal-va-mac-SN38 | 97.87% | Mal-va-mac-SN38 is a drug-linker conjugate for ADC. Mal-va-mac-SN38 contains a ADC cytotoxin SN-38 (HY-13704) and a linker (HY-126364). Mal-va-mac-SN38 can rapidly and covalently bind with endogenous albumin in vivo, resulting in the formation of HSA-va-mac-SN38. Mal-va-mac-SN38 demonstrates exceptional stability in human plasma, and has anti-tumor and anti-metastasis effect. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
