2782024-56-8
Chemical Structure
CRBN ligand-895
- CAS No.: 2782024-56-8
- Formula:C17H21NO5
- Molecular Weight:319.35
InChIKey: UUGJMZNDWTZTIQ-UHFFFAOYSA-N
SMILES: O=C(C(CC1)C2=CC=C(C=C2)OCC(OC(C)(C)C)=O)NC1=O
Biological Activity: CRBN ligand-895 (Compound 14) is an E3 ubiquitin ligase ligand for cereblon (CRBN), which is used to recruit the cereblon protein. CRBN ligand-895 can be used for the synthesis of PROTACs, such as PROTAC HDAC8 Degrader-4 (HY-181024)[1].
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CRBN ligand-895 | CRBN ligand-895 (Compound 14) is an E3 ubiquitin ligase ligand for cereblon (CRBN), which is used to recruit the cereblon protein. CRBN ligand-895 can be used for the synthesis of PROTACs, such as PROTAC HDAC8 Degrader-4 (HY-181024). | |||||||||||||||||||||
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Keywords