2789711-66-4
2789711-66-4
Chemical Structure
Dyrk1A/α-synuclein-IN-2
- CAS No.: 2789711-66-4
- Formula:C21H16N4O4S
- Molecular Weight:420.44
IUPAC Name: 3-hydroxy-N-(4-(3-(6-hydroxybenzo[d]thiazol-2-yl)ureido)phenyl)benzamide
InChIKey: FXJZDPPPJTZRJK-UHFFFAOYSA-N
SMILES: O=C(NC1=NC2=C(S1)C=C(C=C2)O)NC3=CC=C(C=C3)NC(C4=CC(O)=CC=C4)=O
Biological Activity: Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual Dyrk1A and α-synuclein aggregation inhibitor with an IC50 of 7.8 µM for α-synuclein. Dyrk1A/α-synuclein-IN-2 has high predictive CNS penetration and neuroprotective effect[1].
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Dyrk1A/α-synuclein-IN-2 | Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual Dyrk1A and α-synuclein aggregation inhibitor with an IC50 of 7.8 µM for α-synuclein. Dyrk1A/α-synuclein-IN-2 has high predictive CNS penetration and neuroprotective effect. | |||||||||||||||||||||
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References
Keywords
