28002-18-8
Chemical Structure
Sulbenicillin disodium
- CAS No.: 28002-18-8
- Formula:C16H16N2Na2O7S2
- Molecular Weight:458.42
IUPAC Name: sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenyl-2-sulfonatoacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
InChIKey: FWRNIJIOFYDBES-HCIBPFAFSA-L
SMILES: O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(C3=CC=CC=C3)S(=O)(O[Na])=O)=O)N1C2=O)O[Na]
Biological Activity: Sulbenicillin disodium is a semisynthetic α-sulfonylbenzylpenicillin antibiotic. Sulbenicillin disodium exerts antibacterial activity against multiple gram-negative rods. Sulbenicillin disodium inhibits primary and secondary platelet aggregation, serotonin release from platelets, and platelet adherence via platelet surface coating. Sulbenicillin disodium can be used for the research of Pseudomonas aeruginosa, Pseudomonas maltophilia, and Pseudomonas cepacia infections[1][2][3].
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Sulbenicillin disodium | 98.84% | Sulbenicillin disodium is a semisynthetic α-sulfonylbenzylpenicillin antibiotic. Sulbenicillin disodium exerts antibacterial activity against multiple gram-negative rods. Sulbenicillin disodium inhibits primary and secondary platelet aggregation, serotonin release from platelets, and platelet adherence via platelet surface coating. Sulbenicillin disodium can be used for the research of Pseudomonas aeruginosa, Pseudomonas maltophilia, and Pseudomonas cepacia infections. | ||||||||||||||||||||
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- [1]. Hansen IB, et al. Pharmacokinetics of sulbenicillin, a new broad-spectrum semisynthetic penicillin. Clin Pharmacol Ther. 1975;17(3):339-347. [Content Brief]
- [2]. Tsuchiya K, et al. Comparative in vitro activities of SCE-129, sulbenicillin, gentamicin, and dibekacin against Pseudomonas. Antimicrob Agents Chemother. 1978;13(3):536-539. [Content Brief]
- [3]. Ikeda Y, et al. Inhibition of platelet function by sulbenicillin and its metabolite. Antimicrob Agents Chemother. 1978;13(5):881-883. [Content Brief]
Keywords
