2816165-16-7
Chemical Structure
SARS-CoV-2 nsp14-IN-2
- CAS No.: 2816165-16-7
- Formula:C21H21N5O5S
- Molecular Weight:455.49
IUPAC Name: N-(((2R,3S,4R,5S)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)naphthalene-2-sulfonamide
InChIKey: IYCYSBUBGPYWMH-WTGUMLROSA-N
SMILES: O=S(C1=CC=C2C=CC=CC2=C1)(NC[C@H]3O[C@@H](C4=CC=C5C(N)=NC=NN54)[C@H](O)[C@@H]3O)=O
Biological Activity: SARS-CoV-2 nsp14-IN-2 is a potent SARS-CoV-2 Nsp14 methyltransferase inhibitor with an IC50 value of 0.093 µM. SARS-CoV-2 nsp14-IN-2 shows antiviral activity. SARS-CoV-2 nsp14-IN-2 shows plasma and liver S9 stability. SARS-CoV-2 nsp14-IN-2 has the potential for the research of COVID-19[1].
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SARS-CoV-2 nsp14-IN-2 | SARS-CoV-2 nsp14-IN-2 is a potent SARS-CoV-2 Nsp14 methyltransferase inhibitor with an IC50 value of 0.093 µM. SARS-CoV-2 nsp14-IN-2 shows antiviral activity. SARS-CoV-2 nsp14-IN-2 shows plasma and liver S9 stability. SARS-CoV-2 nsp14-IN-2 has the potential for the research of COVID-19. | |||||||||||||||||||||
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Keywords
