2824164-06-7
2824164-06-7
Chemical Structure
Tyk2-IN-26
- CAS No.: 2824164-06-7
- Formula:C23H25N7O2
- Molecular Weight:431.49
InChIKey: MQTVKOFFRJQEQS-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(NC(C2CC2)=O)C=C1NC3=CC=CC4=C3N(C)CC5=CN(C)N=C45)NC
Biological Activity: Tyk2-IN-26 (compound 18) is a TYK2 inhibitor that suppresses TYK2/STAT signaling induced by IL-23 and IFNα, with IC50 values all below 30 nM. Tyk2-IN-26 is applicable to research related to TYK2, IL-23, type I IFN signaling, as well as inflammatory immunity[1].
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Tyk2-IN-26 | Tyk2-IN-26 (compound 18) is a TYK2 inhibitor that suppresses TYK2/STAT signaling induced by IL-23 and IFNα, with IC50 values all below 30 nM. Tyk2-IN-26 is applicable to research related to TYK2, IL-23, type I IFN signaling, as well as inflammatory immunity. | |||||||||||||||||||||
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Voderdeucitinib | Voderdeucitinib (Compoudn I) is a TYK2 inhibitor with an anti-inflammatory activity. Voderdeucitinib can be used for inflammatory and autoimmune disease research, such as rheumatoid arthritis (RA), multiple sclerosis and intestinal bowel disease (IBD). | |||||||||||||||||||||
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References
Keywords
