2839806-94-7
Chemical Structure
(S,R,S)-AHPC-PEG6-Tos
- CAS No.: 2839806-94-7
- Formula:C42H60N4O12S2
- Molecular Weight:877.08
InChIKey: MZDARZRYLYSBLM-HCQVYRIRSA-N
SMILES: C([C@@H](NC(CCOCCOCCOCCOCCOCCOS(=O)(=O)C1=CC=C(C)C=C1)=O)[C@@](C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
Biological Activity: (S, R, S)-AHPC-PEG6-Tos is a combination of a von Hippel-Lindau (VHL)-recruiting ligand and PEGylated crosslinker with a tosyl group. The tosyl group is a good leaving group for nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is useful for synthesis of PROTAC compounds and molecules for targeted protein degradation.
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(S,R,S)-AHPC-PEG6-Tos | (S, R, S)-AHPC-PEG6-Tos is a combination of a von Hippel-Lindau (VHL)-recruiting ligand and PEGylated crosslinker with a tosyl group. The tosyl group is a good leaving group for nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is useful for synthesis of PROTAC compounds and molecules for targeted protein degradation. | |||||||||||||||||||||
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Keywords
