2891692-83-2
Chemical Structure
PI3K/mTOR Inhibitor-12
- CAS No.: 2891692-83-2
- Formula:C27H27F2N9O4S
- Molecular Weight:611.62
IUPAC Name: 2,4-difluoro-N-(2-methoxy-5-(3-(1-(3-morpholinopropyl)-1H-1,2,3-triazol-4-yl)imidazo[1,2-b]pyridazin-6-yl)pyridin-3-yl)benzenesulfonamide
InChIKey: SLVDFWRJWQJSRW-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(F)C=C1F)(NC2=CC(C3=NN4C(C=C3)=NC=C4C5=CN(CCCN6CCOCC6)N=N5)=CN=C2OC)=O
Biological Activity: PI3K/mTOR Inhibitor-12 is a potent, orally active and selective PI3K/mTOR inhibitor with IC50 values of 0.06 nM and 3.12 nM for PI3Kα and mTOR, respectively. PI3K/mTOR Inhibitor-12 has antitumor activity. PI3K/mTOR Inhibitor-12 has lower liver toxicity[1].
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PI3K/mTOR Inhibitor-12 | PI3K/mTOR Inhibitor-12 is a potent, orally active and selective PI3K/mTOR inhibitor with IC50 values of 0.06 nM and 3.12 nM for PI3Kα and mTOR, respectively. PI3K/mTOR Inhibitor-12 has antitumor activity. PI3K/mTOR Inhibitor-12 has lower liver toxicity. | |||||||||||||||||||||
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Keywords
