2918972-18-4
2918972-18-4
Chemical Structure
JQ-1 (carboxylic acid)-NH-C8-COOH
- CAS No.: 2918972-18-4
- Formula:C28H34ClN5O3S
- Molecular Weight:556.12
InChIKey: FDEURZHGKHKLPA-QFIPXVFZSA-N
SMILES: O=C(O)CCCCCCCCNC(C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=C(SC(C)=C3C)N4C1=NN=C4C)=O
Biological Activity: JQ-1 (carboxylic acid)-NH-C8-COOH is a synthetic target protein ligand-conjugate linker, which can be used to synthesize JQ1-S(GlcNAc)Cq (HY-178510). JQ1-S(GlcNAc)Cq is a potent Sugar-Coated PROTAC bifunctional degrader with anti-tumor activity[1].
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JQ-1 (carboxylic acid)-NH-C8-COOH | JQ-1 (carboxylic acid)-NH-C8-COOH is a synthetic target protein ligand-conjugate linker, which can be used to synthesize JQ1-S(GlcNAc)Cq (HY-178510). JQ1-S(GlcNAc)Cq is a potent Sugar-Coated PROTAC bifunctional degrader with anti-tumor activity. | |||||||||||||||||||||
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References
Keywords
