292053-42-0
292053-42-0
Chemical Structure
CCI-006
- CAS No.: 292053-42-0
- Formula:C15H12N2O5S
- Molecular Weight:332.33
IUPAC Name: methyl (E)-2-cyano-3-(5-(4-sulfamoylphenyl)furan-2-yl)acrylate
InChIKey: VEXAKEBSBMAIOB-DHZHZOJOSA-N
SMILES: O=C(/C(C#N)=C/C1=CC=C(C2=CC=C(S(=O)(N)=O)C=C2)O1)OC
Biological Activity: CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCI-006 | 99.87% | CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells. | ||||||||||||||||||||
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References
Keywords
