2922798-57-8
Chemical Structure
Anticancer agent 325
- CAS No.: 2922798-57-8
- Formula:C18H26O5
- Molecular Weight:322.40
IUPAC Name: (10E,12E)-9-hydroperoxyoctadeca-10,12-dienoic acid
InChIKey: VLFWWRDTUMLHTK-UHFFFAOYSA-N
SMILES: OC1=CC=C(OC(C(CCCCC)CC(OC(C)C)=O)=O)C=C1
Biological Activity: Anticancer agent 325 is an apoptosis/autophagy inducer and anticancer agent. Anticancer agent 325 exhibits cytotoxic activity against gastric cancer cells, with no significant effect on healthy gastric epithelial cells. Anticancer agent 325 enhances the expression of activated/cleaved Caspase-3 to promote apoptosis. Anticancer agent 325 also enhances the cleavage of PARP, a downstream marker of apoptosis, promotes LC3B lipidation, and activates autophagy. Anticancer agent 325 can be used in the research of gastric cancer[1].
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Anticancer agent 325 | Anticancer agent 325 is an apoptosis/autophagy inducer and anticancer agent. Anticancer agent 325 exhibits cytotoxic activity against gastric cancer cells, with no significant effect on healthy gastric epithelial cells. Anticancer agent 325 enhances the expression of activated/cleaved Caspase-3 to promote apoptosis. Anticancer agent 325 also enhances the cleavage of PARP, a downstream marker of apoptosis, promotes LC3B lipidation, and activates autophagy. Anticancer agent 325 can be used in the research of gastric cancer. | |||||||||||||||||||||
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Keywords
