2922814-80-8
2922814-80-8
Chemical Structure
NLRP3-IN-28
- CAS No.: 2922814-80-8
- Formula:C12H9F3N2O3S
- Molecular Weight:318.27
InChIKey: BZEQKTJEEFQRQK-UHFFFAOYSA-N
SMILES: O=S(C1=NN=C(C2=C(O)C=C(C(F)(F)F)C=C2)C=C1)(C)=O
Biological Activity: NLRP3-IN-28 (compound N77) is a potent inhibitor of NLRP3. NLRP3-IN-28 inhibits Nigericin (HY-127019)-induced pyroptosis with an EC50 of 0.07μM. NLRP3-IN-28 alleviates the inflammatory reaction in vivo[1].
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NLRP3-IN-28 | NLRP3-IN-28 (compound N77) is a potent inhibitor of NLRP3. NLRP3-IN-28 inhibits Nigericin (HY-127019)-induced pyroptosis with an EC50 of 0.07μM. NLRP3-IN-28 alleviates the inflammatory reaction in vivo. | |||||||||||||||||||||
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References
Keywords
