2924460-80-8
Chemical Structure
TYK2 ligand 2
- CAS No.: 2924460-80-8
- Formula:C24H20FN7O4
- Molecular Weight:489.46
InChIKey: MEHVETCTURCFIZ-UHFFFAOYSA-N
SMILES: COC1=C(C=CC=C1C2=NC=C(C=N2)F)NC3=CC(NC4=CC=C(C=N4)C(O)=O)=NC=C3C(NC)=O
Biological Activity: TYK2 ligand 2 is a TYK2 ligand for TYD-68 (HY-173357). TYD-68 is a highly efficient and selective CRBN-recruited TYK2 PROTAC degrader with a DC50 value of 0.42 nM. TYD-68 can be used in the study of psoriasis[1].
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TYK2 ligand 2 | TYK2 ligand 2 is a TYK2 ligand for TYD-68 (HY-173357). TYD-68 is a highly efficient and selective CRBN-recruited TYK2 PROTAC degrader with a DC50 value of 0.42 nM. TYD-68 can be used in the study of psoriasis. | |||||||||||||||||||||
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Keywords