2925071-06-1
2925071-06-1
Chemical Structure
CRBN ligand-643
- CAS No.: 2925071-06-1
- Formula:C12H10N4O4
- Molecular Weight:274.24
IUPAC Name: 6-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-1H-indazole-3-carboxylic acid
InChIKey: NCEMRAHXHNGYIS-UHFFFAOYSA-N
SMILES: O=C(O)C1=NNC=2C=C(C=CC12)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-643 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-643 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-643 | CRBN ligand-643 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-643 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
