2925079-56-5
Chemical Structure
CRBN ligand-637
- CAS. Nr.: 2925079-56-5
- Formula:C14H11N3O4
- Molecular Weight:285.26
IUPAC Name: 8-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)isoquinoline-4-carboxylic acid
InChIKey: NSFWZUQQPFBSHG-UHFFFAOYSA-N
SMILES: O=C(O)C1=CN=CC=2C1=CC=CC2N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-637 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-637 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-637 | CRBN ligand-637 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-637 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords