2925081-04-3
2925081-04-3
Chemical Structure
CRBN ligand-377
- CAS No.: 2925081-04-3
- Formula:C13H10BrN3O2
- Molecular Weight:320.15
IUPAC Name: 1-(7-bromoisoquinolin-5-yl)dihydropyrimidine-2,4(1H,3H)-dione
InChIKey: AHMWHZYHJZRALZ-UHFFFAOYSA-N
SMILES: O=C1NC(=O)CCN1C2=CC(Br)=CC=3C=NC=CC32
Biological Activity: CRBN ligand-377 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-377 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-377 | CRBN ligand-377 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-377 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
