2925090-99-7
2925090-99-7
Chemical Structure
CRBN ligand-451
- CAS No.: 2925090-99-7
- Formula:C13H10N4O3
- Molecular Weight:270.25
IUPAC Name: 7-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)quinazoline-5-carbaldehyde
InChIKey: GPXILKBVBOEVEI-UHFFFAOYSA-N
SMILES: O=CC=1C=C(C=C2N=CN=CC21)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-451 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-451 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-451 | CRBN ligand-451 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-451 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
