2925100-09-8
2925100-09-8
Chemical Structure
CRBN ligand-757
- CAS No.: 2925100-09-8
- Formula:C13H12N4O4
- Molecular Weight:288.26
IUPAC Name: 7-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-2-methyl-2H-indazole-4-carboxylic acid
InChIKey: SGJTWONJJLIAMD-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(C2=NN(C=C21)C)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-757 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-757 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-757 | CRBN ligand-757 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-757 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords
