2925102-21-0
Chemical Structure
CRBN ligand-621
- CAS. Nr.: 2925102-21-0
- Formula:C14H11N3O4
- Molecular Weight:285.26
IUPAC Name: 5-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)isoquinoline-3-carboxylic acid
InChIKey: JCNVOKRHAHRZLK-UHFFFAOYSA-N
SMILES: O=C(O)C1=NC=C2C=CC=C(C2=C1)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-621 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-621 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-621 | CRBN ligand-621 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-621 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords