2952532-92-0
2952532-92-0
Chemical Structure
IRAK4-IN-28
- CAS No.: 2952532-92-0
- Formula:C27H31N9O3
- Molecular Weight:529.59
InChIKey: YOQDBSNKDCAIOD-UHFFFAOYSA-N
SMILES: CN1N=CC(C2=CC=CC(NC(C3=CC(O4)=C(N=C3N5CCN(C6CC6)CC5)N=C4N7CCOCC7)=O)=N2)=C1
Biological Activity: IRAK4-IN-28 (compound 42) is an orally active IRAK4 inhibitor (IC50=8.9 nM). IRAK4-IN-28 has binding affinity for IRAK4 with a Kd of 0.58 nM. IRAK4-IN-28 can be used in the research of inflammation and autoimmune diseases[1].
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IRAK4-IN-28 | IRAK4-IN-28 (compound 42) is an orally active IRAK4 inhibitor (IC50=8.9 nM). IRAK4-IN-28 has binding affinity for IRAK4 with a Kd of 0.58 nM. IRAK4-IN-28 can be used in the research of inflammation and autoimmune diseases. | |||||||||||||||||||||
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References
Keywords
