2966090-78-6
Chemical Structure
PD-1/PD-L1-IN-26
- CAS No.: 2966090-78-6
- Formula:C43H52N4O8
- Molecular Weight:752.89
IUPAC Name: 2-(hydroxymethyl)-2-((4-((3'-(3-(4-(hydroxymethyl)piperidin-1-yl)propoxy)-2-methyl-[1,1'-biphenyl]-3-yl)methoxy)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)methoxy)benzyl)amino)propane-1,3-diol
InChIKey: JGZQAQGOLLTOQP-UHFFFAOYSA-N
SMILES: CC1=C(C=CC=C1C2=CC=CC(OCCCN3CCC(CC3)CO)=C2)COC4=CC=C(C(OCC5=NN=C(O5)C6=CC=CC=C6)=C4)CNC(CO)(CO)CO
Biological Activity: PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases[1].
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PD-1/PD-L1-IN-26 | PD-1/PD-L1-IN-26 (Compound II-14) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 0.0380 μM. PD-1/PD-L1-IN-26 activates the immune microenvironment by promoting the infiltration of CD4+ T cells into tumor tissues. PD-1/PD-L1-IN-26 has the potential for the research of cancer diseases. | |||||||||||||||||||||
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Keywords
