2982583-44-6

EGFR-IN-101 Chemical Structure
2982583-44-6

Chemical Structure

EGFR-IN-101

  • CAS No.: 2982583-44-6
  • Formula:C35H47N9O2
  • Molecular Weight:625.81

InChIKey: RBGCSMIUHIZHAB-SANMLTNESA-N

SMILES: CN1CCN(C2CCN(C3=CC(OC)=C(NC4=NC=CC(N5C=C(CN[C@@H](C)CO)C(C6=CC=CC=C6)=N5)=N4)C=C3C)CC2)CC1

Biological Activity: EGFR-IN-101 (I-10) is a 2-phenylamino pyrimidine derivative. EGFR-IN-101 is a EGFR inhibitor. The IC50 values for EGFRL858R/T790M/C797S and Ba/F3-EGFRL858R/T790M/C797S are 33.26 and 106.4 nM, respectively. EGFR-IN-101 can be used IN the study of non-small cell lung cancer (NSCLC)[1].

Cat. No. Product Name Purity Description Pricing
HY-161269 		EGFR-IN-101 EGFR-IN-101 (I-10) is a 2-phenylamino pyrimidine derivative. EGFR-IN-101 is a EGFR inhibitor. The IC50 values for EGFRL858R/T790M/C797S and Ba/F3-EGFRL858R/T790M/C797S are 33.26 and 106.4 nM, respectively. EGFR-IN-101 can be used IN the study of non-small cell lung cancer (NSCLC).
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