EGFR-IN-101
EGFR-IN-101 (I-10) is a 2-phenylamino pyrimidine derivative. EGFR-IN-101 is a EGFR inhibitor. The IC50 values for EGFRL858R/T790M/C797S and Ba/F3-EGFRL858R/T790M/C797S are 33.26 and 106.4 nM, respectively. EGFR-IN-101 can be used IN the study of non-small cell lung cancer (NSCLC).
For research use only. We do not sell to patients.
- CAS No.: 2982583-44-6
- Formula: C35H47N9O2
- Molecular Weight:625.81
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All EGFR Isoforms
More
Biological Activity
EGFR[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | IC50 |
106.4 nM
Compound: I-10
|
Antiproliferative activity against mouse BAF3 cells harboring EGFR L858R/T790M/C797S mutant
Antiproliferative activity against mouse BAF3 cells harboring EGFR L858R/T790M/C797S mutant
|
[PMID: 38331226] |
Chemical Information
-
CAS No. 2982583-44-6
-
Molecular Weight 625.81
-
Formula C35H47N9O2
-
SMILES
CN1CCN(C2CCN(C3=CC(OC)=C(NC4=NC=CC(N5C=C(CN[C@@H](C)CO)C(C6=CC=CC=C6)=N5)=N4)C=C3C)CC2)CC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR-IN-101 Related Classifications
HY-161269 Related Classifications
Powered by Bioz