2988566-71-6
Chemical Structure
Hcyb1
- CAS No.: 2988566-71-6
- Formula:C24H20N4O
- Molecular Weight:380.44
IUPAC Name: 2-benzyl-9-(1-(naphthalen-1-yl)ethyl)-1,9-dihydro-6H-purin-6-one
InChIKey: CJQKPYUNZSUCKT-UHFFFAOYSA-N
SMILES: O=C1NC(CC2=CC=CC=C2)=NC3=C1N=CN3C(C)C4=C5C=CC=CC5=CC=C4
Biological Activity: Hcyb1 is a highly selective, orally active PDE2 inhibitor. Hcyb1 has a highly selective inhibition of PDE2A (IC50=0.57 μM) and over 250-fold selectivity against other recombinant PDE family members. Hcyb1 produces neuroprotective and antidepressant‐like effects most likely mediated by cAMP/cGMP-CREB-BDNF signaling[1].
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Hcyb1 | 98.20% | Hcyb1 is a highly selective, orally active PDE2 inhibitor. Hcyb1 has a highly selective inhibition of PDE2A (IC50=0.57 μM) and over 250-fold selectivity against other recombinant PDE family members. Hcyb1 produces neuroprotective and antidepressant‐like effects most likely mediated by cAMP/cGMP-CREB-BDNF signaling. | ||||||||||||||||||||
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Keywords