3004967-41-0
3004967-41-0
Chemical Structure
FAK-IN-20
- CAS No.: 3004967-41-0
- Formula:C27H34ClN7O5S
- Molecular Weight:604.12
InChIKey: XRDCURCMOBUNGQ-HDICACEKSA-N
SMILES: O=C(NC)C1=CC=CC=C1NC2=C(Cl)C=NC(NC3=C(OC)C=C(NS(CCN4C[C@@H](C)O[C@@H](C)C4)(=O)=O)C=C3)=N2
Biological Activity: FAK-IN-20 (Compound 7b) is an inhibitor of FAK with an IC50 value of 0.27 nM. FAK-IN-20 exhibits anticancer activity. FAK-IN-20 can arrest the cell cycle in the G2/M phase and induce cell apoptosis by generating ROS[1].
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FAK-IN-20 | FAK-IN-20 (Compound 7b) is an inhibitor of FAK with an IC50 value of 0.27 nM. FAK-IN-20 exhibits anticancer activity. FAK-IN-20 can arrest the cell cycle in the G2/M phase and induce cell apoptosis by generating ROS. | |||||||||||||||||||||
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References
Keywords
