3018150-80-3
3018150-80-3
Chemical Structure
FLT3-ITD-IN-3
- CAS No.: 3018150-80-3
- Formula:C27H21ClF2N6O5
- Molecular Weight:582.94
InChIKey: XSEYQSRWZIREBU-UHFFFAOYSA-N
SMILES: O=C(C(C(C)=C1)=NN(C2=CC(Cl)=CC=C2F)C1=O)NC3=CC=C(OC4=CC(NC(N5CC(O)C5)=O)=NC=C4)C(F)=C3
Biological Activity:
FLT3-ITD-IN-3 (13v), an orally active FLT3-ITD (FLT3 internal tandem duplication) inhibitor, disrupts FLT3 signal transduction and induced G0/G1 cell cycle arrest and apoptosis. FLT3-ITD-IN-3 (13v) is used in the research of acute myeloid leukemia (AML)[1].
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FLT3-ITD-IN-3 | FLT3-ITD-IN-3 (13v), an orally active FLT3-ITD (FLT3 internal tandem duplication) inhibitor, disrupts FLT3 signal transduction and induced G0/G1 cell cycle arrest and apoptosis. FLT3-ITD-IN-3 (13v) is used in the research of acute myeloid leukemia (AML). |
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References
Keywords
