3024292-21-2
Chemical Structure
PROTAC PDIA1 degrader 1
- CAS No.: 3024292-21-2
- Formula:C40H44N6O12S
- Molecular Weight:832.88
SMILES: COC1=C(N(C(C#C)=O)C(C(NCC(NCCOCCOCCOCCNC2=C(C(N(C3C(NC(CC3)=O)=O)C4=O)=O)C4=CC=C2)=O)=O)C5=CC=CS5)C=CC(OC)=C1
Biological Activity: PROTAC PDIA1 degrader 1 (Compound H4) is a PDIA1 PROTAC degrader with a DC50 of 29.71 μM. PROTAC PDIA1 degrader 1 has potent anticancer activity and significantly inhibits cancer cell proliferation[1]. Pink: PDIA1 ligand (HY-100433); Blue: CRBN ligase ligand (HY-10984); Black: linker (HY-W015088)
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PROTAC PDIA1 degrader 1 | PROTAC PDIA1 degrader 1 (Compound H4) is a PDIA1 PROTAC degrader with a DC50 of 29.71 μM. PROTAC PDIA1 degrader 1 has potent anticancer activity and significantly inhibits cancer cell proliferation. Pink: PDIA1 ligand (HY-100433); Blue: CRBN ligase ligand (HY-10984); Black: linker (HY-W015088) | |||||||||||||||||||||
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Keywords