3024922-89-9
3024922-89-9
Chemical Structure
VEGFR2/HDAC1-IN-1
- CAS No.: 3024922-89-9
- Formula:C27H30N4O7
- Molecular Weight:522.55
InChIKey: MQCKWGOUUCDJTC-UHFFFAOYSA-N
SMILES: CC1=C(C(NC)=O)C(C=C2)=C(O1)C=C2OC3=NC=NC4=CC(OC)=C(OCCCCCCC(NO)=O)C=C43
Biological Activity: VEGFR2/HDAC1-IN-1 (compound 13) is a potent VEGFR-2/HDAC dual inhibitor, with IC50s of 57.83 nM and 9.82 nM, respectively. VEGFR2/HDAC1-IN-1 arrests the cell cycle at the S and G2 phases, and induces apoptosis in HeLa cells. VEGFR2/HDAC1-IN-1 exhibits anti-angiogenic effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
VEGFR2/HDAC1-IN-1 | VEGFR2/HDAC1-IN-1 (compound 13) is a potent VEGFR-2/HDAC dual inhibitor, with IC50s of 57.83 nM and 9.82 nM, respectively. VEGFR2/HDAC1-IN-1 arrests the cell cycle at the S and G2 phases, and induces apoptosis in HeLa cells. VEGFR2/HDAC1-IN-1 exhibits anti-angiogenic effect. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
