VEGFR2/HDAC1-IN-1
VEGFR2/HDAC1-IN-1 (compound 13) is a potent VEGFR-2/HDAC dual inhibitor, with IC50s of 57.83 nM and 9.82 nM, respectively. VEGFR2/HDAC1-IN-1 arrests the cell cycle at the S and G2 phases, and induces apoptosis in HeLa cells. VEGFR2/HDAC1-IN-1 exhibits anti-angiogenic effect.
For research use only. We do not sell to patients.
- CAS No.: 3024922-89-9
- Formula: C27H30N4O7
- Molecular Weight:522.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All VEGFR Isoforms
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Biological Activity
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VEGFR-2 57.83 nM (IC50) |
HDAC 9.82 nM (IC50) |
Chemical Information
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CAS No. 3024922-89-9
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Molecular Weight 522.55
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Formula C27H30N4O7
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SMILES
CC1=C(C(NC)=O)C(C=C2)=C(O1)C=C2OC3=NC=NC4=CC(OC)=C(OCCCCCCC(NO)=O)C=C43
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VEGFR2/HDAC1-IN-1 Related Classifications
HY-149630 Related Classifications
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