3025234-94-7
Chemical Structure
α-Glucosidase-IN-36
- CAS. Nr.: 3025234-94-7
- Formula:C26H24BrN5O3S
- Molecular Weight:566.47
InChIKey: TZFDWOPPBNUDLO-LQKURTRISA-N
SMILES: BrC1=CC=C(/C=N/N2C(COC3=CC=CC=C3)=NN=C2SCC(NC4=CC=C(OCC)C=C4)=O)C=C1
Biological Activity: α-Glucosidase-IN-36 (compound 5g) is a potent α-glucosidase inhibitor, with an IC50 of 6.69 ± 0.18 μM, Ki and Kis of 1.65 μM and 4.54 μM, respectively. α-Glucosidase-IN-36 may inhibit α-glucosidase activity by binding with its active site as well as changing the secondary structure of α-glucosidase. α-Glucosidase-IN-36 can be used for type 2 diabetes mellitus (T2DM) research[1].
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α-Glucosidase-IN-36 | α-Glucosidase-IN-36 (compound 5g) is a potent α-glucosidase inhibitor, with an IC50 of 6.69 ± 0.18 μM, Ki and Kis of 1.65 μM and 4.54 μM, respectively. α-Glucosidase-IN-36 may inhibit α-glucosidase activity by binding with its active site as well as changing the secondary structure of α-glucosidase. α-Glucosidase-IN-36 can be used for type 2 diabetes mellitus (T2DM) research. | |||||||||||||||||||||
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Keywords
