3026842-89-4
3026842-89-4
Chemical Structure
(3S)Lenalidomide-5-Pip-Boc
- CAS No.: 3026842-89-4
- Formula:C22H28N4O5
- Molecular Weight:428.48
InChIKey: DANIYVQIRXOIKI-KRWDZBQOSA-N
SMILES: O=C(OC(C)(C)C)N1CCN(CC1)C2=CC3=C(C=C2)C(N(C3)[C@H](C(N4)=O)CCC4=O)=O
Biological Activity: (3S) Lenalidomide-5-Pip-Boc is an E3 ligase ligand-linker conjugate that is applicable to research related to PROTAC synthesis. (3S) Lenalidomide-5-Pip-Boc serves as the E3 ligase ligand-linker conjugate for PROTAC ERα Degrader-10 (HY-170336) and PROTAC ER Degrader-14 (HY-170340)[1][2].
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(3S)Lenalidomide-5-Pip-Boc | (3S) Lenalidomide-5-Pip-Boc is an E3 ligase ligand-linker conjugate that is applicable to research related to PROTAC synthesis. (3S) Lenalidomide-5-Pip-Boc serves as the E3 ligase ligand-linker conjugate for PROTAC ERα Degrader-10 (HY-170336) and PROTAC ER Degrader-14 (HY-170340). | |||||||||||||||||||||
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References
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[1]. Fan J, et al. Novel compounds having estrogen receptor alpha degradation activity and uses thereof. US20200157078A1, United States Patent and Trademark Office, 2020.
- [2]. Fan J, et al. Chroman derivatives having estrogen receptor degradation activity and uses thereof. US10800770B1, United States Patent and Trademark Office, 2020.
Keywords
