3032270-35-9
3032270-35-9
Chemical Structure
PD-1/PD-L1-IN-39
- CAS No.: 3032270-35-9
- Formula:C23H20ClFN2O3
- Molecular Weight:426.87
InChIKey: YAHBFTAUXKIAHZ-UHFFFAOYSA-N
SMILES: ClC1=C(C=CC=C1C2=C(C=CC=C2)F)COC3=NC4=C(C=C3)CN(CC(O)=O)CC4
Biological Activity: PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with a IC50 value of 15.73 nM. PD-1/ PD-L1-in-39 has a good binding affinity for human and mouse PD-L1, with KD values of 14.62 nM and 392 nM, respectively. PD-1/PD-L1-IN-39 has antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PD-1/PD-L1-IN-39 | PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with a IC50 value of 15.73 nM. PD-1/ PD-L1-in-39 has a good binding affinity for human and mouse PD-L1, with KD values of 14.62 nM and 392 nM, respectively. PD-1/PD-L1-IN-39 has antitumor activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
