3032621-10-3
3032621-10-3
Chemical Structure
PARP-1/HDAC-IN-1
- CAS No.: 3032621-10-3
- Formula:C22H18N4O4
- Molecular Weight:402.40
IUPAC Name: 2-(4-((4-(hydroxycarbamoyl)benzyl)oxy)phenyl)-2H-indazole-7-carboxamide
InChIKey: KASIRBSNIZZVJQ-UHFFFAOYSA-N
SMILES: NC(C1=CC=CC2=CN(N=C21)C3=CC=C(C=C3)OCC4=CC=C(C=C4)C(NO)=O)=O
Biological Activity: PARP-1/HDAC-IN-1 is a PARP-1/HDAC6 dual targeting inhibitor with IC50s of 68.90 nM and 510 nM, respectively. PARP-1/HDAC-IN-1 displays remarkable anticancer, anti-migration and anti-angiogenesis activities[1].
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PARP-1/HDAC-IN-1 | PARP-1/HDAC-IN-1 is a PARP-1/HDAC6 dual targeting inhibitor with IC50s of 68.90 nM and 510 nM, respectively. PARP-1/HDAC-IN-1 displays remarkable anticancer, anti-migration and anti-angiogenesis activities. | |||||||||||||||||||||
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References
Keywords
