3032667-94-7
Chemical Structure
NCA029
- CAS No.: 3032667-94-7
- Formula:C22H20F3N3O
- Molecular Weight:399.41
InChIKey: WFISMZGRGBWALP-UHFFFAOYSA-N
SMILES: N#CC1=CC=CC(CN2CCC=C(C2)C(NCC3=CC=C(C=C3)C(F)(F)F)=O)=C1
Biological Activity: NCA029 is a potent and selective homo sapiens caseinolytic protease P (HsClpP) activator with an EC50 of 0.15 μM. NCA029 acts on HsClpP to activate an ATF3-dependent integrative stress response, leading to colon cancer cell death[1].
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NCA029 | 98.24% | NCA029 is a potent and selective homo sapiens caseinolytic protease P (HsClpP) activator with an EC50 of 0.15 μM. NCA029 acts on HsClpP to activate an ATF3-dependent integrative stress response, leading to colon cancer cell death. | ||||||||||||||||||||
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Keywords