3032850-37-3

PROTAC BRD4 Degrader-22 Chemical Structure
3032850-37-3

Chemical Structure

PROTAC BRD4 Degrader-22

  • CAS No.: 3032850-37-3
  • Formula:C38H41ClN8O5S
  • Molecular Weight:757.30

InChIKey: BIVJJLVZJPBUMK-XIJSCUBXSA-N

SMILES: O=C(C1=CC=C(C=C1OC)N2CCC(CC2)CNC(C[C@@H]3N=C(C4=C(N5C(C)=NN=C35)SC(C)=C4C)C6=CC=C(C=C6)Cl)=O)NC(C(N7)=O)CCC7=O

Biological Activity: PROTAC BRD4 Degrader-22 is a BRD4 PROTAC degrader with a DC50 of 0.59 nM. At high concentrations, PROTAC BRD4 Degrader-22 induces partial degradation of BRD3 and BRD2, but exhibits selectivity for IKZF3. PROTAC BRD4 Degrader-22 can be used in leukemia-related research[1].

Cat. No. Product Name Purity Description Pricing
HY-155393 		PROTAC BRD4 Degrader-22 PROTAC BRD4 Degrader-22 is a BRD4 PROTAC degrader with a DC50 of 0.59 nM. At high concentrations, PROTAC BRD4 Degrader-22 induces partial degradation of BRD3 and BRD2, but exhibits selectivity for IKZF3. PROTAC BRD4 Degrader-22 can be used in leukemia-related research.
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